The menopause transition typically begins between 40 and 50 years of age average Osteoporosis can be minimized by smoking cessation , adequate vitamin D intake and regular weight-bearing exercise. The transition has a variable degree of effects. After menopause, estrogen continues to be produced mostly by aromatase in fat tissues and is produced in small amounts in many other tissues such as ovaries, bone, blood vessels, and the brain where it acts locally. This is a medical calque ; the Greek word for menses is actually different. In addition, this change often occurs when other stressors may be present in a woman's life: Low-dose prescription vaginal estrogen products such as estrogen creams are generally a safe way to use estrogen topically, to help vaginal thinning and dryness problems see vaginal atrophy while only minimally increasing the levels of estrogen in the bloodstream. The main cause of this transition is the natural depletion and aging of the finite amount of oocytes ovarian reserve.
Raloxifene prevents vertebral fractures in postmenopausal, osteoporotic women and reduces the risk of invasive breast cancer. During perimenopause approaching menopause , estradiol levels and patterns of production remain relatively unchanged or may increase compared to young women, but the cycles become frequently shorter or irregular. Therefore, a reasonably long stretch of time is necessary to be sure that the cycling has ceased. The functional disorders often significantly speed up the menopausal process. Ovarian aging[ edit ] Decreased inhibin feedback after hysterectomy is hypothesized to contribute to increased ovarian stimulation and earlier menopause. The official date is determined retroactively, once 12 months have passed after the last appearance of menstrual blood. Reduced blood supply to the ovaries that may occur as a consequence of hysterectomy and uterine artery embolisation has been hypothesized to contribute to this effect. In contrast to the sudden fall in estradiol during menopause, the levels of total and free testosterone, as well as dehydroepiandrosterone sulfate DHEAS and androstenedione appear to decline more or less steadily with age. In addition, this change often occurs when other stressors may be present in a woman's life: Other factors that can promote an earlier onset of menopause usually 1 to 3 years early are smoking cigarettes or being extremely thin. An effect of natural menopause on circulating androgen levels has not been observed. A woman's reproductive hormone levels continue to drop and fluctuate for some time into post-menopause, so hormone withdrawal effects such as hot flashes may take several years to disappear. The word "menopause" was coined specifically for human females, where the end of fertility is traditionally indicated by the permanent stopping of monthly menstruations. Individual counseling or support groups can sometimes be helpful to handle sad, depressed, anxious or confused feelings women may be having as they pass through what can be for some a very challenging transition time. Meiosis is the general process by which germ cells are formed in all sexual eukaryotes; it appears to be an adaptation for efficiently removing damages in germ line DNA. Thus postmenopause is the time in a woman's life that takes place after her last period or, more accurately, after the point when her ovaries become inactive. Primordial follicles are immature primary oocytes surrounded by a single layer of granulosa cells. Management[ edit ] Perimenopause is a natural stage of life. This is a medical calque ; the Greek word for menses is actually different. The main cause of this transition is the natural depletion and aging of the finite amount of oocytes ovarian reserve. Low-dose prescription vaginal estrogen products such as estrogen creams are generally a safe way to use estrogen topically, to help vaginal thinning and dryness problems see vaginal atrophy while only minimally increasing the levels of estrogen in the bloodstream. A period-like flow during postmenopause, even spotting, may be a sign of endometrial cancer. It is worth pointing out that moisturizers and lubricants are different products for different issues: Women with early diagnosis and treatment of coeliac disease present a normal duration of fertile life span. At this point a woman is considered infertile; however, the possibility of becoming pregnant has usually been very low but not quite zero for a number of years before this point is reached.
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AT WHAT AGE SHOULD YOU HAVE SEX
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